About the Role
At Naring Health, our mission is to empower everyone to access individualized clinical and molecular data to manage and make informed decisions about their health proactively. As a multiomics research scientist, you will apply state-of-the-art mass spectrometry-based analytical approaches to biomarker discovery efforts across multiple chronic diseases that affect millions of patients worldwide. You will use your expertise in analytical instrumentation and protein/proteome or metabolite/metabolome characterization to move the program’s technical base forward. This will include new technology assessments and the development of standard -omics assays in untargeted and targeted formats. You will work closely with data scientists and machine learning engineers to build cutting-edge platforms in the -omics space that provide novel biological insight and mechanistic detail underlying challenging chronic disease states. Together, we will make regular health monitoring, early disease detection, and personalized care a reality for every individual, improving lives and transforming healthcare along the way.
High-level responsibilities for this role:
Immediately take a technical leadership role on projects involving large-scale, high-throughput proteomic and/or metabolomic biomarker discovery in the chronic disease space.
Provide expert guidance and collaborative input on experimental design and proteomics and/or metabolomics assay development and optimization for untargeted and targeted formats.
Stay up-to-date with the field and continually assess novel approaches that could be deployed in-house to move our technical program forward.
Calibrate, maintain, and track the performance of LC-MS instrumentation, and help establish best practices for these activities in the lab.
Collaborate effectively with data scientists and engineers to integrate molecular technologies at the bench with next-generation computational and informatics pipelines.
What you’ll bring to the table:
Ph.D. or master’s degree (or equivalent industry experience) in biochemistry, analytical chemistry, or a related field with specific expertise in mass spectrometry-based proteomics, metabolomics, or lipidomics.
0+ years (Scientist) or 3+ years (Senior Scientist) of full-time laboratory experience in either proteomics or metabolomics laboratory research (industry and/or academia/post-doc) after final degree completion
Proven track record in developing and implementing mass spectrometry-based -omics workflows, specifically:
Strong working knowledge of high-performance liquid chromatography (HPLC) instrumentation and method development (especially Agilent, Thermo Fisher, and/or EvoSep systems).
Strong working knowledge of sample preparation workflows in proteomics, metabolomics and/or lipidomics (experience working with complex biological matrices such as plasma/serum/urine is preferred).
Strong working knowledge of contemporary mass spectrometry instrumentation, including system maintenance, troubleshooting, and optimization (especially QQQ, QTof, and Orbitrap-based systems).
Extensive experience with protein and/or metabolite identification, characterization, and quantitation using LC-MS, including familiarity with standard computational tools in the field (e.g., MaxQuant, Proteome Discoverer, Scaffold, etc.)
Experience in data-independent acquisition (DIA) and/or SWATH workflows would be advantageous for this position.
Ability to perform basic MS data processing and analysis to enable experimental iteration independent of external support.
While not required, competency in a standard scientific programming language (e.g., Python or R) would be advantageous for this position.
Strong communication skills, eagerness to collaborate with researchers from different disciplines, and a comfort level with the flexibility and dynamic nature of working at an early-stage start-up
Physical Demands and Work Environment:
The physical demands described here represent those that an employee must meet to perform the essential functions of this position successfully. Reasonable accommodations may enable individuals with disabilities to perform the functions.
The ability to alternate between sitting and standing is present when a worker has the flexibility to choose between sitting or standing as needed.
Entering text or data into a computer or other machine using a traditional keyboard.
Must be able to lift at least 25 lbs occasionally
Must be fully vaccinated and boosted for COVID-19
About the Company
Naring Health provides comprehensive Digital Health & Wellness services that pair Precision Nutrition and Multiomics Diagnostic technologies to better manage chronic disease.
Equal Opportunity Employment: Naring Health is an equal opportunity employer, harassment-free workplace, and complies with ADA regulations as applicable. All applicants are considered for all positions without regard to race, religion, color, sex, gender, sexual orientation, pregnancy, age, national origin, ancestry, physical/mental disability, medical condition, military/veteran status, genetic information, marital status, ethnicity, or any other protected characteristic, in accordance with applicable federal, state, and local laws.